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By mutating residues at the dimerization interface, weaker dimers which had a higher affinity for ubiquitin were produced. The weak dimers had an increased population of monomer at equilibrium. A phosphorylation site at Ser403 in p62 UBA was recently identified.

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steriods 7MbAbstractA study of kaon production in high energy nucleon air nucleus collisions in the atmosphere; has been made based on the muon momentum spectrum at sea level. Starting from the measured vertical momentum spectrum the spectra at zenith angles between 75 and 90 have been predicted for various admixtures: of kaons and pions, taking into account all decay modes: of both charged and neutral kaons. The predicted values are compared with the intensities measured using the Durham horizontal muon spectrographs Although the method of computation allows the spectra to be predicted to an accuracy of 1% the present statistical errors on both the vertical and horizontal intensities are such that only an upper limit to R, the ratio of intensities at production of kaons to pions of all charge states, can be given; this has a value of about kOfo over a range of mesoa energies from about 70 G eV to 1000 GeV. steriods

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