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If, however, the interim analysis is negative, she expects the

New drugs drive prostate cancer market

canada goose store LOS ANGELES (Reuters) Options for treating prostate cancer are expanding with the advent of novel, canada goose and more expensive, medicines, with key data expected soon for what could be one of the biggest new drugs. canada goose store

canada goose black friday sale After surgery or radiation, prostate cancer patients are typically treated with canadian goose jacket drugs, like Lupron, that uk canada goose trick the testicles into ceasing production of testosterone, the male hormone that fuels prostate cancer cell growth. canada goose black friday sale

canada goose deals Better understanding of the molecular abnormalities underlying the disease has led to new approaches, including Johnson Johnson Zytiga, which works inside cancer cells to block testosterone production, and Dendreon Corp Provenge, a therapeutic vaccine designed to canada goose clearance spur the body immune system to attack malignant cells. canada goose deals

canadian goose jacket Decision Resources, a healthcare advisory firm, expects global sales canada goose coats on sale of prostate cancer drugs to more than double from nearly $4 billion in 2009 to $8.9 billion in 2019. canadian goose jacket

now have more effective agents targeting the androgen (testosterone) receptor, said Dr. Elizabeth Plimack, an oncologist at Philadelphia Fox Chase Cancer Center. some point all patients will probably be completely resistant to these drugs. ultimately we need a new approach.

Medivation Inc is developing Canada Goose sale a drug, canada goose uk outlet known as MDV3100, designed to interfere with the ability of testosterone to bind to prostate cells.

Canada Goose Parka KEY MEDIVATION DATA AWAITED Full results from a pivotal trial of MDV3100 are due next year, but there is widespread debate over whether an Canada Goose Coats On Sale interim analysis expected before the end of this year might prove that MDV3100 is effective buy canada goose jacket cheap and the trial could be canada goose coats stopped early. Canada Goose Parka

canada goose clearance If that happens, shares of Medivation which closed at $18.94 on Monday would jump to $30 or $35, according to Citigroup analyst Lucy Lu. If, however, the interim analysis is negative, she expects the stock to fall below $10. canada goose clearance

is certainly promising. but we haven seen the data cheap Canada Goose yet, said Dr. Plimack.

Optimism Canada Goose Parka about the Medivation trial Canada Goose Online centers on the fact that J pivotal trial of Zytiga, which had shown similar cheap canada goose uk efficacy in earlier studies, was stopped as soon as it became clear that the drug improved survival.

canada goose clearance sale Investor interest in Medivation has waned since March 2010, when the company announced the failure of a Phase 3 trial for its experimental Alzheimer drug. canada goose clearance sale

Canada Goose online Wall Street analysts, on average, expect the company sales of MDV3100 to reach $297 million by 2015, with sales by development partner Astellas Pharma forecast at $89 million, according to Thomson Reuters data. Canada Goose online

Canada Goose Outlet J Zytiga sales, which have exceeded expectations since the drug approval Canada Goose online in April, are forecast to https://www.canadagooseonline.org reach $815 million by 2015. Canada Goose Outlet

canada goose PROVENGE SALES UNCERTAIN The sales trajectory canada goose uk shop for Provenge remains uncertain. Analysts expect 2015 sales of nearly $1.3 billion, but that is canada goose uk black friday down sharply from a nearly $2 billion average Canada Goose Jackets estimate before Dendreon stunned investors in August by withdrawing canada goose clearance sale its own sales forecast because it was taking longer than expected for doctors to become comfortable with reimbursement issues. canada goose

Canada Goose Jackets is very exciting because it is the first immunotherapy for prostate canada goose black friday sale cancer, uk canada goose outlet but it is fraught with logistical issues, Dr. Plimack said. are nervous to take on the cost in case reimbursement doesn come through. Canada Goose Jackets

Canada Goose sale A course of treatment with Provenge costs $93,000, while Zytiga costs $5,000 a month, usually for eight cycles. Canada Goose sale

canada goose coats New York canada goose factory sale area oncologists and urologists polled in a recent focus group conducted by Sanford Bernstein said Zytiga and others drugs in the same Canada Goose Outlet class will be used in as many as 40 percent of patients by 2015, hormonal therapies will still be used in up to 90 percent of patients, and anti androgens like MDV3100 would be canada goose coats used in 70 percent to 80 percent of men buy canada goose jacket with prostate cancer. canada goose coats

canada goose coats on sale Bernstein said both groups of doctors expect Provenge to be used in up to 12 percent of patients. canada goose coats on sale

buy canada goose jacket cheap Prostate cancer kills about 250,000 men a year globally and is the second most common cause of cancer death in men in the United States, after lung cancer. buy canada goose jacket cheap

cheap Canada Goose Over the longer term, drugmakers aim to move new therapies into earlier lines of treatment, possibly helping patients avoid side effects, like medical castration, that are common with canada goose store current hormone altering drugs or to reduce the need for harsh chemotherapy treatments. cheap Canada Goose

buy canada goose jacket In addition to MDV3100, prostate cancer medicines under development include custirsen from OncoGenex Pharmaceuticals Inc and Exelixis Inc cabozatinib. buy canada goose jacket

For supportive care, Amgen Inc Xgeva prevents fractures and other bone problems in cancer patients and the company is seeking to expand its use to reduce the risk of bone metastases in certain prostate cancer patients.

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